Author

M. Bortolozzi

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Biophysics· 2 Biochemistry· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:experimental assay· 3 Assay:cryo-EM· 2 Organism:human· 2 Research Focus:protein structure prediction· 2 Research Focus:cell signaling & trafficking· 1 Approach:deep learning· 1 Assay:imaging· 1 Organism:mouse· 1

Frequent Co-Authors

C. Qi· 2 shared D. Schuster· 2 shared E. Bayraktar· 2 shared P. Lavriha· 2 shared P. Picotti· 2 shared V. M. Korkhov· 2 shared A. Othman· 1 shared A. Vaithia· 1 shared

Activity by Year

2021-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 28 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

2 shared papersBiophysics

C. Qi

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Structures of wild-type and selected CMT1X mutant connexin 32 gap junction channels and hemichannels

C. Qi, P. Lavriha, E. Bayraktar, A. Vaithia, D. Schuster, M. Pannella, V. Sala, P. Picotti, M. Bortolozzi, V. M. Korkhov

The paper presents cryo-EM structures of wild-type and CMT1X mutant connexin 32 gap junction channels and hemichannels, revealing a gating helix defect in disease-associated mutants.

bioRxiv · Mar 8, 2023Biophysics

Structure of the connexin-43 gap junction channel in a putative closed state

C. Qi, S. Acosta-Gutierrez, P. Lavriha, A. Othman, D. Lopez-Pigozzi, E. Bayraktar, D. Schuster, P. Picotti, N. Zamboni, M. Bortolozzi, F. L. Gervasio, V. M. Korkhov

The paper determines the structure of a human Cx43 gap junction channel in a closed state using cryo-EM, revealing a previously unknown conformation stabilized by a small molecule.

bioRxiv · Mar 26, 2022Biochemistry

Calcium signaling in the photodamaged skin

V. Donati, C. Peres, C. Nardin, F. Scavizzi, M. Raspa, C. D. Ciubotaru, M. Bortolozzi, F. Mammano

This study investigates Ca2+ wave propagation in photodamaged murine epidermis, finding that ATP release from damaged cells drives intercellular Ca2+ waves via P2Y receptors.

bioRxiv · May 14, 2021 · PreprintBiophysics