Relative abundance data can misrepresent heritability of the microbiome
M. Bruijning, J. F. Ayroles, L. P. Henry, B. Koskella, K. M. Meyer, C. J. E. Metcalf
This paper shows that using relative abundance data to estimate microbiome heritability can lead to imprecise, overestimated, and biased results due to taxon interdependencies, large sample sizes, and microbial co-abundances.
bioRxiv · Apr 26, 2022Evolutionary Biology