Loss of IL-10 signaling promotes IL-22 dependent host defenses against acute Clostridioides difficile infection
E. S. Cribas, J. E. Denny, J. R. Maslanka, M. C. Abt
The paper shows that loss of IL-10 signaling increases IL-22-dependent host defenses, reducing mortality from C. difficile infection in mice.
bioRxiv · Oct 14, 2020Immunology