Nucleotide inhibition of the pancreatic ATP-sensitive K+ channel explored with patch-clamp fluorometry
S. Usher, F. M. Ashcroft, M. C. Puljung
The paper investigates how nucleotides inhibit pancreatic KATP channels using patch-clamp fluorometry, revealing SUR1's dual role in nucleotide binding and stabilizing the closed state.
bioRxiv · Oct 15, 2019Biophysics