CED-5/CED-12 (DOCK/ELMO) can promote and inhibit F-actin formation via distinct motifs that target different GTPases
T. Venkatachalam, S. Mannimala, M. C. Soto
The paper identifies that CED-5/CED-12 can both promote and inhibit F-actin formation by acting as a GEF for Rac1 and a GAP for CDC-42/RHO-1 during different cellular processes.
bioRxiv · Oct 4, 2023 · PreprintCell Biology