Author

M. C. Virgilio

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Assay:proteomics· 1

Frequent Co-Authors

A. Lubin· 1 shared B. Ramnani· 1 shared C. A. Hockings· 1 shared C. Böiers· 1 shared E. M. Payne· 1 shared J. D. Welch· 1 shared J. Lubow· 1 shared J. Rowell· 1 shared

Activity by Year

2020-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperCancer Biology

A. Lubin

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2 papers

Recent·Most cited

HIV-1 Vpr combats the PU.1-driven antiviral response in primary human macrophages.

M. C. Virgilio, B. Ramnani, T. Chen, W. M. Disbennett, J. Lubow, J. D. Welch, K. L. Collins

This study shows HIV-1 Vpr suppresses PU.1 to reduce antiviral immune responses in macrophages, facilitating viral spread.

bioRxiv · Mar 21, 2023Microbiology

TLR7 ligation augments haematopoiesis in Rps14 (uS11) deficiency via paradoxical suppression of inflammatory signalling and enhanced differentiation

O. C. Pena, A. Lubin, J. Rowell, C. A. Hockings, Y. Jung, Y. Hoade, P. Dace, L. E. Valdivia, K. Tuschl, C. Böiers, M. C. Virgilio, S. Richardson, E. M. Payne

This study identifies imiquimod, a TLR7 agonist, as a therapeutic for MDS by enhancing haematopoiesis through paradoxical anti-inflammatory effects and increased differentiation.

bioRxiv · Jul 6, 2020Cancer Biology