Short-term exposure to intermittent hypoxia leads to changes in gene expression seen in chronic pulmonary disease
G. Wu, Y. Y. Lee, E. M. Gulla, A. Potter, J. Kitzmiller, M. D. Ruben, N. Salomonis, J. A. Whitsett, L. J. Francey, J. B. Hogenesch, D. F. Smith
This study shows that intermittent hypoxia in mice alters gene expression in lung cells, particularly in endothelial cells, linking it to pulmonary fibrosis and hypertension pathways.
bioRxiv · Mar 6, 2020Pathology