Author

Y. Y. Lee

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 2 Cell Biology· 1 Pathology· 1 Plant Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 4 Approach:experimental assay· 4 Organism:mouse· 3 Assay:proteomics· 3 Research Focus:differential expression· 2 Approach:statistical model· 2 Research Focus:benchmarking· 1 Assay:bulk RNA-seq· 1

Frequent Co-Authors

B. L. Schulz· 2 shared C. Aitken· 2 shared C. B. Howard· 2 shared D. Roche Recinos· 2 shared L. F. Zacchi· 2 shared V. Sandford· 2 shared A. Noureen· 1 shared A. Olave-Achury· 1 shared

Activity by Year

2018-2022 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 16 mutual co-author links

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2 shared papersBiochemistry

B. L. Schulz

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

The Solanum americanum pangenome and effectoromics reveal new resistance genes against potato late blight

X. Lin, Y. Jia, R. Heal, M. Prokchorchik, M. Sindalovskaya, A. Olave-Achury, M. Makechemu, S. Fairhead, A. Noureen, J. Heo, K. Witek, M. Smoker, J. Taylor, R.-K. Shrestha, Y. Y. Lee, , J. D. Jones

The paper identifies novel resistance genes in Solanum americanum against Phytophthora infestans by analyzing genome variation and effector recognition.

bioRxiv · Aug 11, 2022Plant Biology

Analysis of coagulation factor IX in bioreactor cell culture medium predicts yield and quality of the purified product

L. F. Zacchi, D. Roche Recinos, C. L. Pegg, T. K. Phung, M. Napoli, C. Aitken, V. Sandford, S. M. Mahler, Y. Y. Lee, B. L. Schulz, C. B. Howard

The paper uses DIA-MS proteomics to predict rFIX yield and quality by analyzing bioreactor supernatant, identifying PTMs and their impact on purification and function.

bioRxiv · Jun 3, 2020Biochemistry

Short-term exposure to intermittent hypoxia leads to changes in gene expression seen in chronic pulmonary disease

G. Wu, Y. Y. Lee, E. M. Gulla, A. Potter, J. Kitzmiller, M. D. Ruben, N. Salomonis, J. A. Whitsett, L. J. Francey, J. B. Hogenesch, D. F. Smith

This study shows that intermittent hypoxia in mice alters gene expression in lung cells, particularly in endothelial cells, linking it to pulmonary fibrosis and hypertension pathways.

bioRxiv · Mar 6, 2020Pathology

S-Trap eliminates cell culture media polymeric surfactants for effective proteomic analysis of mammalian cell bioreactor supernatants

L. F. Zacchi, D. Roche Recinos, E. Otte, C. Aitken, T. Hunt, V. Sandford, Y. Y. Lee, B. L. Schulz, C. B. Howard

This study compares sample preparation methods to remove polymeric surfactants from bioreactor supernatants, finding S-Trap provides the best clean-up and data quality.

bioRxiv · Feb 17, 2020Biochemistry

Dietary fatty acids promote lipid droplet diversity through seipin enrichment in an ER subdomain

Z. Cao, Y. Hao, Y. Y. Lee, P. Wang, X. Li, K. Xie, W. J. Lam, Y. Qiu, G. Shui, P. Liu, J. Qu, B.-H. Kang, H. Y. Mak

The paper shows dietary fatty acids influence lipid droplet diversity via SEIP-1 enrichment in an ER subdomain in C. elegans and mammalian cells.

bioRxiv · Sep 22, 2018Cell Biology