Cell BiologybioRxiv
A novel bioreactor technology for modelling fibrosis in human and rodent precision-cut liver slices.
H. Paish, L. Reed, H. Brown…·F. Oakley
This paper develops a bioreactor system that extends the viability of precision-cut liver slices (PCLS) to 6 days under normoxic conditions and demonstrates its use in modeling fibrogenesis and testing anti-fibrotic drugs.