Sonic Hedgehog Activates Prostaglandin Signaling to Stabilize Primary Cilium Length
S. S. Ansari, M. E. Dillard, Y. Zhang, M. A. Austria, N. Boatwright, E. L. Shelton, A. Johnson, B. M. Young, Z. Rankovic, J. D. Schuetz, C. G. Robinson, S. K. Ogden
This study shows SHH signaling stabilizes primary cilium length through crosstalk with EP4 prostaglandin signaling, ensuring proper SHH pathway function.
bioRxiv · May 6, 2022Cell Biology