Designer DNA architecture offers precise and multivalent spatial pattern-recognition for viral sensing and inhibition
P. S. Kwon, S. Ren, S.-J. Kwon, M. E. Kizer, L. Kuo, F. Zhou, F. Zhang, D. Kim, K. Fraser, L. D. Kramer, N. C. Seeman, J. S. Dordick, R. J. Linhardt, J. Chao, X. Wang
The paper designs a DNA nanostructure that recognizes and inhibits dengue virus through precise spatial arrangement of aptamers, enabling sensitive and rapid sensing and inhibition.
bioRxiv · Apr 13, 2019Bioengineering