Endocytosis is regulated through the pH-dependent phosphorylation of Rab GTPases by Parkinson's kinase LRRK2
M. E. Maxson, K. Huynh, S. Grinstein
This study shows that LRRK2 kinase phosphorylates Rab GTPases in response to pH changes, affecting endocytic vacuole formation and vesicular traffic.
bioRxiv · Feb 15, 2023 · PreprintCell Biology