Author

M. E. Metcalf

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Biophysics· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Organism:E. coli· 1 Research Focus:host-pathogen & immune response· 1 Approach:mechanistic / dynamical model· 1

Frequent Co-Authors

A. K. Vasan· 1 shared D. Shukla· 1 shared E. Tajkhorshid· 1 shared N. Haloi· 1 shared P. J. Hergenrother· 1 shared P.-C. Wen· 1 shared R. J. Ulrich· 1 shared W. W. Metcalf· 1 shared

Activity by Year

2021-2021 · peak 1/yr

Co-Author Collaboration Network

8 top collaborators · 28 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

1 shared paperBiophysics

A. K. Vasan

Mutual co-authors in cluster

Author profile →

1 paper

Recent·Most cited

Investigation of gating in outer membrane porins provides new perspectives on antibiotic resistance mechanisms

A. K. Vasan, N. Haloi, R. J. Ulrich, M. E. Metcalf, P.-C. Wen, W. W. Metcalf, P. J. Hergenrother, D. Shukla, E. Tajkhorshid

This study uses molecular dynamics simulations and experiments to show that dynamic gating of E. coli outer membrane porin OmpF, mediated by conserved acidic residues, regulates antibiotic permeability and contributes to antibiotic resistance.

bioRxiv · Sep 9, 2021 · PreprintBiophysics