Author

R. J. Ulrich

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biophysics· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Research Focus:host-pathogen & immune response· 2 Organism:bacteria (other)· 1 Research Focus:cell signaling & trafficking· 1 Organism:E. coli· 1 Approach:experimental assay· 1 Approach:mechanistic / dynamical model· 1 Assay:metabolomics· 1 Approach:microscopy & imaging analysis· 1

Frequent Co-Authors

A. DuMont· 1 shared A. F. Haag· 1 shared A. I. Perault· 1 shared A. K. Vasan· 1 shared A. Pironti· 1 shared A. Pountain· 1 shared A. R. Richardson· 1 shared B. Shopsin· 1 shared

Activity by Year

2021-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 36 mutual co-author links

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1 shared paperMicrobiology

A. DuMont

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

Quorum-sensing agr system of Staphylococcus aureus primes gene expression for protection from lethal oxidative stress

M. Podkowik, A. I. Perault, G. Putzel, A. Pountain, J. Kim, A. DuMont, E. Zwack, R. J. Ulrich, T. K. Karagounis, C. Zhou, A. F. Haag, J. Shenderovich, G. A. Wasserman, J. Kwon, J. Chen, , B. Shopsin

This study shows that the agr quorum-sensing system in Staphylococcus aureus primes the bacteria to resist oxidative stress by controlling reactive oxygen species, even when the system is not actively activated.

bioRxiv · Jun 8, 2023 · PreprintMicrobiology

Investigation of gating in outer membrane porins provides new perspectives on antibiotic resistance mechanisms

A. K. Vasan, N. Haloi, R. J. Ulrich, M. E. Metcalf, P.-C. Wen, W. W. Metcalf, P. J. Hergenrother, D. Shukla, E. Tajkhorshid

This study uses molecular dynamics simulations and experiments to show that dynamic gating of E. coli outer membrane porin OmpF, mediated by conserved acidic residues, regulates antibiotic permeability and contributes to antibiotic resistance.

bioRxiv · Sep 9, 2021 · PreprintBiophysics