Knockout of E-cadherin in adult mouse epithelium results in emphysema and airway disease
B. Ghosh, J. Loube, S. Thapa, E. Capodanno, S. Mahmud, M. Girgis, S. Chen, K. Nishida, L. Ying, C. Swaby, A. Wally, D. R. Bhowmik, M. E. Zaykaner, W. Mitzner, V. K. Sidhaye
This study shows that loss of E-cadherin in adult mouse lung epithelium causes emphysema and airway disease, suggesting a causal role in COPD.
bioRxiv · Jul 18, 2021 · PreprintCell Biology