The Loss of the E3 ubiquitin ligase TRIP12 inhibits Pancreatic Acinar Cell Plasticity and Tumor Cell Metastatic Capacity
M. Brunet, C. Vargas, M. Fanjul, L. Pieruccioni, D. Varry, G. Labrousse, H. Lulka, F. Capilla, A. Couvelard, V. Gigoux, J. Guillermet-Guibert, J. Torrisani, M. Dufresne
This paper shows that TRIP12 loss inhibits pancreatic acinar cell plasticity and tumor metastasis by affecting Claudin18.2 expression and ADM.
bioRxiv · Mar 8, 2023 · PreprintCancer Biology