Author

C. Vargas

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 2 Cancer Biology· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Research Focus:cell type annotation· 2 Assay:proteomics· 2 Assay:bulk RNA-seq· 1 Research Focus:differential expression· 1 Organism:human· 1 Organism:mouse· 1 Research Focus:protein folding & dynamics· 1

Frequent Co-Authors

S. Keller· 2 shared A. Couvelard· 1 shared A. E. Marcoleta· 1 shared A. Meister· 1 shared B. Danielczak· 1 shared C. Chu· 1 shared C. Kolar· 1 shared D. Rojas· 1 shared

Activity by Year

2021-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 11 mutual co-author links

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2 shared papersBiochemistry

S. Keller

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Capturing G protein-coupled receptors into native lipid-bilayer nanodiscs using new diisobutylene/maleic acid (DIBMA) copolymers

C. Chu, C. Vargas, M. C. Barbosa, S. Sommerhage, G. F. Schroeder, S. Keller, M. Etzkorn

This paper introduces new DIBMA-based copolymers for extracting GPCRs into native lipid-bilayer nanodiscs, showing improved performance over existing polymers like SMA.

bioRxiv · Jan 20, 2024Biochemistry

Effects of Polyphosphate metabolism Mutations on Biofilm, Capsule Formation and Virulence Traits in Hypervirulent ST23 Klebsiella pneumoniae SGH10

D. Rojas, A. E. Marcoleta, M. Galvez-Silva, M. A. Varas, M. Diaz, M. Hernandez, C. Vargas, G. Nourdin, E. Koch, P. Saldivia, J. Vielma, Y.-H. Gan, Y. Chen, N. Guiliani, F. P. Chavez

This study examines how mutations in polyphosphate metabolism affect biofilm, capsule formation, and virulence in hypervirulent Klebsiella pneumoniae using a model host.

bioRxiv · Sep 15, 2023 · PreprintMicrobiology

The Loss of the E3 ubiquitin ligase TRIP12 inhibits Pancreatic Acinar Cell Plasticity and Tumor Cell Metastatic Capacity

M. Brunet, C. Vargas, M. Fanjul, L. Pieruccioni, D. Varry, G. Labrousse, H. Lulka, F. Capilla, A. Couvelard, V. Gigoux, J. Guillermet-Guibert, J. Torrisani, M. Dufresne

This paper shows that TRIP12 loss inhibits pancreatic acinar cell plasticity and tumor metastasis by affecting Claudin18.2 expression and ADM.

bioRxiv · Mar 8, 2023 · PreprintCancer Biology

A Bioinspired Glycopolymer for Capturing Membrane Proteins in Native-Like Lipid-Bilayer Nanodiscs

B. Danielczak, M. Rasche, J. Lenz, E. Perez Patallo, S. Weyrauch, F. Mahler, M. T. Agbadaola, A. Meister, J. O. Babalola, C. Vargas, C. Kolar, S. Keller

This paper introduces Glyco-DIBMA, a bioinspired glycopolymer that improves the efficiency of forming nanodiscs for membrane proteins compared to existing aliphatic copolymers.

bioRxiv · Mar 31, 2021Biochemistry