Leaky severe combined immunodeficiency in mice lacking non-homologous end joining factors XLF and MRI
S. Castaneda-Zegarra, Q. Zhang, A. Alirezaylavasani, M. Fernandez-Berrocal, R. Yao, V. Oksenych
This study shows that XLF is functionally redundant with MRI and PAXX in lymphocyte development, and Mri interacts genetically with Dna-pkcs and Paxx in mice.
bioRxiv · Mar 4, 2020Immunology