Illumination of a progressive allosteric mechanism mediating the glycine receptor activation
S. Shi, S. N. Lefebvre, L. Peverini, A. H. Cerdan, M. Gielen, J.-P. Changeux, M. CECCHINI, P.-J. Corringer
The paper uses fluorescence and simulations to reveal a progressive conformational change in the glycine receptor that precedes channel activation.
bioRxiv · Jun 4, 2022Biophysics