Immune sensing of food allergens promotes aversive behaviour
E. B. Florsheim, N. D. Bachtel, J. Cullen, B. G. Costa Lima, M. Godazgar, C. Zhang, F. Carvalho, G. Gautier, P. Launay, A. Wang, M. O. Dietrich, R. Medzhitov
This study shows that immune sensing of food allergens drives antigen-specific behavioural aversion in mice, involving IgE, mast cells, and leukotrienes, and extends to lipopolysaccharide-induced inflammation.
bioRxiv · Jan 19, 2023 · PreprintImmunology