R. Medzhitov

This study identifies macrophage-derived Oncostatin M as a critical regulator of type I interferon responses during viral respiratory infection, preventing excessive inflammation.

This study shows that immune sensing of food allergens drives antigen-specific behavioural aversion in mice, involving IgE, mast cells, and leukotrienes, and extends to lipopolysaccharide-induced inflammation.

This study shows fibroblasts sense space and regulate macrophage numbers via growth factor production.

This study shows that hepatic FGF21 promotes survival during bacterial inflammation by preserving cardiac function, and its signaling via beta-Klotho is required for this protective effect.

This study shows adiponectin and related CTRP proteins bind to anionic phospholipids and sphingolipids, suggesting they function as lipid-binding opsonins or carriers.