Author

M. Guma

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Cell Biology· 1

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Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Organism:human· 1 Organism:mouse· 1 Approach:statistical model· 1

Frequent Co-Authors

A. Cheng· 1 shared A. J. Lana· 1 shared A. Torres· 1 shared C. K. Glass· 1 shared E. Lopez· 1 shared I. Cobo· 1 shared J. Saich· 1 shared J. Schlachetzki· 1 shared

Activity by Year

2021-2021 · peak 1/yr

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10 top collaborators · 45 mutual co-author links

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1 shared paperCell Biology

A. Cheng

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1 paper

Recent·Most cited

Monosodium Urate Crystals regulate a unique JNK-dependent macrophage metabolic and inflammatory response

I. Cobo, A. Cheng, J. Saich, R. Coras, A. Torres, A. J. Lana, J. Schlachetzki, R. Bryan, R. Terkeltaub, E. Lopez, C. K. Glass, M. Guma

This study shows that monosodium urate crystals induce a unique JNK-dependent metabolic and inflammatory response in macrophages, distinct from LPS, and that JNK inhibition reduces inflammation in gout models.

bioRxiv · Apr 14, 2021Cell Biology