Author

i. Cobo

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 2

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 2 Organism:human· 2 Organism:mouse· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

A. Torres· 2 shared A. Cheng· 1 shared A. J. Lana· 1 shared C. K. Glass· 1 shared E. Lopez· 1 shared F. Garcia· 1 shared F. X. Real· 1 shared I. Millan· 1 shared

Activity by Year

2021-2021 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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2 shared papersCell Biology

A. Torres

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2 papers

Recent·Most cited

NFIC regulates ribosomal biology and ER stress in pancreatic acinar cells and suppresses PDAC initiation

i. Cobo, S. Paliwal, J. Melia-Aloma, A. Torres, J. Martinez-Villarreal, F. Garcia, I. Millan, N. del Pozo, J.-C. Park, R. J. MacDonald, J. Munoz, F. X. Real

This study identifies NFIC as a regulator of acinar cell differentiation and ER stress, showing its role in suppressing pancreatic ductal adenocarcinoma initiation.

bioRxiv · Aug 9, 2021 · PreprintCell Biology

Monosodium Urate Crystals regulate a unique JNK-dependent macrophage metabolic and inflammatory response

I. Cobo, A. Cheng, J. Saich, R. Coras, A. Torres, A. J. Lana, J. Schlachetzki, R. Bryan, R. Terkeltaub, E. Lopez, C. K. Glass, M. Guma

This study shows that monosodium urate crystals induce a unique JNK-dependent metabolic and inflammatory response in macrophages, distinct from LPS, and that JNK inhibition reduces inflammation in gout models.

bioRxiv · Apr 14, 2021Cell Biology