Finding Druggable Sites in Proteins using TACTICS
D. J. Evans, R. A. Yovanno, S. Rahman, D. W. Cao, M. Q. Beckett, M. H. Patel, A. F. Bandak, A. Y. Lau
TACTICS identifies druggable sites in proteins using molecular dynamics data, clustering, random forest, and fragment docking, predicting novel binding sites in SARS-CoV-2 and Yersinia pestis proteins.
bioRxiv · Feb 21, 2021Biophysics