Using energy to go downhill - a genoprotective role for ATPase activity in DNA topoisomerase II
A. F. Bandak, T. R. Blower, K. c. Nitiss, V. Shah, J. L. Nitiss, J. M. Berger
This study shows that ATPase activity in type II topoisomerases prevents excessive DNA damage by regulating strand passage and cleavage.
bioRxiv · Jun 27, 2023Biochemistry