Cancer BiologybioRxiv
MYCN Amplification and ATRX Mutations are Incompatible in Neuroblastoma
M. Zeineldin, S. Federico, X. Chen…·M. Dyer
The paper shows that ATRX mutations and MYCN amplification are mutually exclusive in neuroblastoma and lead to synthetic lethality.
DOI 10.1038/s41467-020-14682-6