Author

M. Zeineldin

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Cancer Biology· 3 Cell Biology· 1 Pathology· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:experimental assay· 4 Organism:human· 4 Research Focus:cancer & tumor microenvironment· 3 Assay:organoid / primary culture· 2 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Assay:ChIP-seq· 1 Research Focus:chromatin & epigenetic regulation· 1

Frequent Co-Authors

B. Xu· 2 shared J. Zhu· 2 shared R. Li· 2 shared T. C. Larman· 2 shared Y. Dong· 2 shared A. Bahrami· 1 shared A. K. Meeker· 1 shared A. Liu· 1 shared

Activity by Year

2018-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 17 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

2 shared papersCancer Biology

B. Xu

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

Disruption of Epithelium Integrity by Inflammation-Associated Fibroblasts through Prostaglandin Signaling

Y. Dong, B. A. Johns, L. Ruan, M. Zeineldin, A. Liu, S. Raychaudhuri, I. Chiu, J. Zhu, B. Smith, N. Zhao, P. Searson, S. Watanabe, M. Donowitz, T. C. Larman, R. Li

This study shows inflammation-associated fibroblasts disrupt colon epithelial barrier integrity and genome stability via PGE2-EP4 signaling, and EP4 inhibitors can reverse these effects.

Science Advances · Apr 5, 2024Peer-reviewedCell Biology

SATB2 loss in inflammatory bowel disease-associated small intestinal metaplasia of the distal colon

M. Zeineldin, T. C. Larman

The paper shows SATB2 loss is associated with preneoplastic metaplasia in IBD-related chronic colitis, linking it to small intestinal metaplasia and increased cancer risk.

bioRxiv · Feb 1, 2023 · PreprintPathology

The TERT promoter is polycomb-repressed in neuroblastoma cells with long telomeres

M. K. Graham, B. Xu, C. Davis, A. K. Meeker, C. M. Heaphy, S. Yegnasubramanian, M. A. Dyer, M. Zeineldin

This study shows that TERT promoter hypomethylation and chromatin state differ in neuroblastoma based on telomere maintenance mechanisms, with repressive marks in long telomere-associated cells.

bioRxiv · May 18, 2022Cancer Biology

Colonic epithelial adaptation to EGFR-independent growth induces induces chromosomal instability and is accelerated by prior injury

T. Chen, M. Zeineldin, B. Johnson, Y. Dong, A. Narkar, T. Li, J. Zhu, R. Li, T. Larman

This study shows that colonic epithelial cells adapt to EGFR-independent growth, leading to chromosomal instability and accelerated by prior injury, without introducing cancer driver mutations.

bioRxiv · Feb 2, 2021Cancer Biology

MYCN Amplification and ATRX Mutations are Incompatible in Neuroblastoma

M. Zeineldin, S. Federico, X. Chen, Y. Fan, B. Xu, E. Stewart, X. Zhou, J. Jeon, L. Griffiths, J. Easton, H. Mulder, D. Yergeau, Y. Liu, J. Wu, C. Van Ryn, , M. Dyer

The paper shows that ATRX mutations and MYCN amplification are mutually exclusive in neuroblastoma and lead to synthetic lethality.

bioRxiv · Jul 29, 2018Cancer Biology