Nodavirus RNA Replication Crown Architecture Reveals Proto-Crown Precursor and Viral Protein A Conformational Switching
H. Zhan, N. Unchwaniwala, A. Rebolledo-Viveros, J. Pennington, M. Horswill, R. Broadberry, J. Myers, J. A. den Boon, T. Grant, P. Ahlquist
The paper uses cryo-EM to reveal the structure of nodavirus RNA replication crowns, identifying a proto-crown precursor and conformational changes in viral protein A.
Proceedings of the National Academy of Sciences · Jan 24, 2023Peer-reviewedMicrobiology