Author

M. I. Miller

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioengineering· 3 Neuroscience· 1

Signature Assays, Organisms & Methods

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Approach:statistical model· 4 Organism:human· 3 Assay:spatial transcriptomics· 3 Research Focus:cell type annotation· 2 Approach:deep learning· 2 Assay:imaging· 2 Research Focus:spatial domain detection· 2 Research Focus:benchmarking· 1

Frequent Co-Authors

D. J. Tward· 3 shared A. Trouve· 2 shared K. Stouffer· 2 shared M. Witter· 2 shared C. Ceritoglu· 1 shared C. Chen· 1 shared E. Xu· 1 shared H. Zeng· 1 shared

Activity by Year

2021-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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3 shared papersBioengineering

D. J. Tward

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Author profile →

4 papers

Recent·Most cited

A Universal Method for Crossing Molecular and Atlas Modalities using Simplex-Based Image Varifolds and Quadratic Programming

K. M. Stouffer, A. Trouve, L. Younes, M. Kunst, L. Ng, H. Zeng, M. Anant, J. Fan, Y. Kim, M. I. Miller

This paper introduces a method to align molecular transcriptomics data with tissue atlases using geometric and optimization techniques, enabling integration of diverse datasets into a common coordinate system.

bioRxiv · Mar 28, 2023 · PreprintBioengineering

Amygdalar and ERC Rostral Atrophy and Tau Pathology Reconstruction in Preclinical Alzheimer's Disease

K. Stouffer, C. Chen, S. Kulason, E. Xu, M. Witter, C. Ceritoglu, M. Albert, S. Mori, J. Troncoso, D. J. Tward, M. I. Miller

This study measures amygdala and ERC atrophy rates in preclinical Alzheimer's disease using MRI and reconstructs 3D tau pathology distributions, finding amygdala atrophy comparable to ERC and suggesting it as a potential biomarker.

bioRxiv · Jun 6, 2022 · PreprintBioengineering

Projective LDDMM: Mapping Molecular Digital Pathology with Tissue MRI

K. Stouffer, M. Witter, D. J. Tward, M. I. Miller

This paper introduces Projective LDDMM, a method mapping dense MRI atlases to sparse histological measurements, with applications in Alzheimer's biomarker development.

bioRxiv · Apr 22, 2022 · PreprintBioengineering

Hierarchical Computational Anatomy: Unifying the Molecular to Tissue Continuum via Measure Representations of the Brain

M. I. Miller, D. J. Tward, A. Trouve

This paper introduces a unified framework for brain mapping that integrates molecular and tissue scales using geometric measure representations, applied to Alzheimer's disease.

bioRxiv · Apr 19, 2021 · PreprintNeuroscience