BiochemistrybioRxiv
A Dual-Site Inhibitor of CBP/p300 KIX is a Selective and Effective Modulator of Myb
S. T. Joy, M. J. Henley, S. N. De Salle…·A. Mapp
This paper develops a dual-site inhibitor, MybLL-tide, that selectively targets the CBP/p300 KIX domain, inhibiting Myb-dependent gene expression in AML cells.
DOI 10.1021/jacs.1c04432