Author

M. J. Guertin

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Assay:DNA methylation· 1 Assay:proteomics· 1

Frequent Co-Authors

A. B. Dutta· 1 shared A. Spencer· 1 shared D. E. Frigo· 1 shared D. G. Roller· 1 shared D. Gioeli· 1 shared K. M. Sathyan· 1 shared P. Przanowski· 1 shared R. K. Przanowska· 1 shared

Activity by Year

2021-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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1 shared paperCancer Biology

A. B. Dutta

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2 papers

Recent·Most cited

The androgen receptor does not directly regulate the transcription of DNA damage response genes

S. Hasterok, T. G. Scott, D. G. Roller, A. Spencer, A. B. Dutta, K. M. Sathyan, D. E. Frigo, M. J. Guertin, D. Gioeli

This study investigates whether the androgen receptor directly regulates DNA damage response gene transcription in prostate cancer cells and finds it does not.

bioRxiv · May 13, 2023Cancer Biology

ANKLE1 cleaves mitochondrial DNA and contributes to cancer risk by promoting apoptosis resistance and metabolic dysregulation

P. Przanowski, R. K. Przanowska, M. J. Guertin

This study identifies ANKLE1 as a causal gene in the chr19p13.1 locus associated with cancer risk, showing it promotes apoptosis resistance and metabolic dysregulation through mitochondrial DNA cleavage.

bioRxiv · Oct 27, 2021Cancer Biology