Siglec-5 is an inhibitory immune checkpoint molecule for human T cells
A. Vuchkovska, D. Glanville, G. Scurti, P. White, M. I. Nishimura, A. Ulijasz, M. J. Iwashima
This study identifies Siglec-5 as an inhibitory checkpoint molecule on activated human T cells that suppresses TCR-mediated activation and effector functions.
bioRxiv · Jan 4, 2022Immunology