FHOD-1/profilin-mediated actin assembly protects sarcomeres against contraction-induced deformation in C. elegans
M. J. Kimmich, S. Sundaramurthy, M. A. Geary, L. Lesanpezeshki, C. V. Yingling, S. A. Vanapalli, R. S. Littlefield, D. Pruyne
This study shows FHOD-1 and profilin cooperate to stabilize sarcomere Z-lines in C. elegans by promoting actin assembly and preventing muscle deformation during contraction.
bioRxiv · Feb 29, 2024 · PreprintCell Biology