Local membrane charge regulates β2 adrenergic receptor coupling to Gi
M. J. Strohman, S. Maeda, D. Hilger, M. Masureel, Y. Du, B. K. Kobilka
This study shows that local membrane charge affects β2AR coupling to Gi and Gs proteins, with negative charges inhibiting Gi coupling and promoting Gs coupling.
bioRxiv · Aug 25, 2018Biochemistry