M. J. Tamas

Adaptation of the yeast gene knockout collection is near-perfectly predicted by fitness and diminishing return epistasis

This study shows that fitness predicts adaptation dynamics in yeast gene knockouts under arsenic exposure, with diminishing return epistasis explaining the predictability.

Nuclear envelope budding is a response to cellular stress

The paper shows nuclear envelope budding increases in response to cellular stress in yeast, suggesting a role in protein quality control.

Genome-wide imaging screen uncovers molecular determinants of arsenite-induced protein aggregation and toxicity and an important role for transcriptional and translational control

The paper identifies molecular factors involved in arsenite-induced protein aggregation and toxicity using a genome-wide imaging screen in yeast, showing the importance of transcriptional and translational control in proteostasis.