Hepatocytic Prominin-1 protects against liver fibrosis by stabilizing the SMAD7 protein
H. Lee, D.-M. Yu, M. J. Um, S. Y. Yoon, K.-T. Kim, Y. J. Kwon, S. Lee, M.-S. Bahn, S.-H. Koo, K. H. Jung, J.-S. Lee, Y.-G. Ko
This study shows that hepatocytic Prominin-1 prevents liver fibrosis by stabilizing SMAD7, thereby inhibiting TGFβ signaling.
bioRxiv · Nov 19, 2019 · PreprintCell Biology