Humanized CYP2C19 transgenic mouse as an animal model of cerebellar ataxia
F. Milosavljević, Irene Brusini, A. Atanasov, M. Manojlović, Maria Novalen, M. Vučić, Zorana Oreščanin-Dušić, Jelena Brkljačić, Sharon L. Miksys, Č. Miljević, Aleksandra Nikolic, Duško Blagojević, Chunliang Wang, Peter Damberg, Pešić Vesna, , M. Jukić
This study characterizes the motoric phenotype of CYP2C19 transgenic mice and finds reduced cerebellar volume and impaired motor function, suggesting a model for cerebellar ataxia.
Neuroscience Applied · Jan 1, 2022Peer-reviewedNeuroscience