Chunliang Wang

Humanized CYP2C19 transgenic mouse as an animal model of cerebellar ataxia

This study characterizes the motoric phenotype of CYP2C19 transgenic mice and finds reduced cerebellar volume and impaired motor function, suggesting a model for cerebellar ataxia.

MRI-derived brain age as a biomarker of ageing in rats: validation using a healthy lifestyle intervention

The paper develops a rat brain age prediction algorithm using MRI and validates it through a healthy lifestyle intervention, showing reduced brain ageing with environmental enrichment and dietary restriction.

Objective Evaluation of Multiple Sclerosis Lesion Segmentation using a Data Management and Processing Infrastructure

This paper evaluates MS lesion segmentation algorithms using a new open-science infrastructure, finding that automatic methods lag behind human experts in detection and delineation.