Author

M. K. Thorsen

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Biology Disciplines

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Microbiology· 1

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Approach:biophysical modeling· 1 Research Focus:host-pathogen & immune response· 1 Organism:virus· 1

Frequent Co-Authors

A. Lai· 1 shared D. P. Hoogerheide· 1 shared E. E. Heldwein· 1 shared G. C. L. Wong· 1 shared J. H. Freed· 1 shared M. W. Lee· 1 shared

Activity by Year

2021-2021 · peak 1/yr

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6 top collaborators · 15 mutual co-author links

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1 shared paperMicrobiology

A. Lai

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1 paper

Recent·Most cited

Highly basic clusters in the HSV-1 nuclear egress complex drive membrane budding by inducing lipid ordering

M. K. Thorsen, A. Lai, M. W. Lee, D. P. Hoogerheide, G. C. L. Wong, J. H. Freed, E. E. Heldwein

This study identifies how basic regions in the HSV-1 nuclear egress complex induce lipid ordering and negative curvature to drive membrane budding, with phosphorylation inhibiting this process.

bioRxiv · May 18, 2021Microbiology