Author

G. C. L. Wong

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 5

Signature Assays, Organisms & Methods

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Organism:bacteria (other)· 4 Research Focus:cell signaling & trafficking· 3 Approach:experimental assay· 3 Approach:statistical model· 2 Approach:biophysical modeling· 1 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:development & morphogenesis· 1

Frequent Co-Authors

J. de Anda· 3 shared C. K. Lee· 2 shared C. R. Armbruster· 2 shared D. A. Hogan· 2 shared G. A. O'Toole· 2 shared K. A. Lewis· 2 shared M. R. Parsek· 2 shared A. Baker· 1 shared

Activity by Year

2019-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 28 mutual co-author links

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3 shared papersMicrobiology

J. de Anda

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Author profile →

5 papers

Recent·Most cited

How individual P. aeruginosa cells with diverse stator distributions collectively form a heterogeneous macroscopic swarming population

J. de Anda, S. Kuchma, S. S. Webster, A. Boromand, K. A. Lewis, C. Lee, M. Contreras, V. F. Medeiros Pereira, D. A. Hogan, C. O'Hern, G. A. O'Toole, G. C. L. Wong

The paper shows that P. aeruginosa cells with different stator distributions create a heterogeneous swarming population through dynamic stator recruitment and motor intermittency.

mBio · Apr 10, 2024Peer-reviewedMicrobiology

Highly basic clusters in the HSV-1 nuclear egress complex drive membrane budding by inducing lipid ordering

M. K. Thorsen, A. Lai, M. W. Lee, D. P. Hoogerheide, G. C. L. Wong, J. H. Freed, E. E. Heldwein

This study identifies how basic regions in the HSV-1 nuclear egress complex induce lipid ordering and negative curvature to drive membrane budding, with phosphorylation inhibiting this process.

bioRxiv · May 18, 2021Microbiology

Fine tuning cyclic-di-GMP signaling in Pseudomonas aeruginosa using the type 4 pili alignment complex

S. Webster, C. K. Lee, W. Schmidt, G. C. L. Wong, G. O'Toole

This paper identifies PilO's role in modulating SadC activity to regulate cyclic-di-GMP levels and biofilm formation in Pseudomonas aeruginosa.

bioRxiv · Oct 17, 2020 · PreprintMicrobiology

Phenotypic differences in reversible attachment behavior reveal distinct P. aeruginosa surface colonization strategies

C. K.-m. Lee, J. Vachier, J. de Anda, k. zhao, A. Baker, R. R. Bennett, C. R. Armbruster, K. A. Lewis, R. L. Tarnopol, C. J. Lomba, D. A. Hogan, M. R. Parsek, G. A. O'Toole, R. Golestanian, G. C. L. Wong

The paper examines reversible attachment behavior in P. aeruginosa strains PAO1 and PA14, revealing distinct surface colonization strategies through single-cell tracking and stochastic modeling.

bioRxiv · Oct 10, 2019 · PreprintMicrobiology

Heterogeneity in surface sensing produces a division of labor in Pseudomonas aeruginosa populations

C. R. Armbruster, C. K. Lee, J. Parker-Gilham, J. de Anda, A. Xia, B. S. Tseng, L. R. Hoffman, F. Jin, C. Harwood, G. C. L. Wong, M. R. Parsek

This study shows that Pseudomonas aeruginosa develops two subpopulations with distinct c-di-GMP levels after surface attachment, leading to a division of labor in biofilm formation and surface exploration.

bioRxiv · Jan 29, 2019Microbiology