Laminin α1 orchestrates VEGFA functions in the ecosystem of colorectal carcinoma
E. Mammadova-Bach, T. Rupp, C. Spenle, I. Jivkov, P. P. Shankaranarayanan, A. Klein, L. Pisarsky, A. Mechine-Neuville, G. Cremel, M. Kedinger, O. De Wever, N. Ambartsumian, S. Robine, E. Pencreach, D. Guenot, , O. Lefebvre
This study shows that laminin α1 promotes colon tumor growth by facilitating VEGFA-driven angiogenesis through interactions with integrin β1 and CXCR4.
bioRxiv · Jan 10, 2017Cancer Biology