UNC-45 has a crucial role in maintaining muscle sarcomeres during aging in C. elegans
C. J. Matheny, H. Qadota, M. Kimelman, A. O. Bailey, A. F. Oberhauser, G. Benian
This study shows that UNC-45 is essential for maintaining muscle sarcomeres in C. elegans during aging, with its loss leading to sarcopenia through myosin degradation.
bioRxiv · Jun 4, 2022 · PreprintCell Biology