H. Qadota

FARL-11 (STRIP1/2) is Required for Sarcomere and Sarcoplasmic Reticulum Organization in C. elegans

This study shows that STRIP1 is essential for sarcoplasmic reticulum and sarcomere organization in C. elegans muscle.

The Rho GAP RRC-1 is required for the assembly or stability of integrin adhesion complexes and is a member of the PIX pathway in muscle

The paper identifies RRC-1 as a Rho GAP in the PIX pathway required for integrin adhesion complex assembly and stability in C. elegans muscle.

UNC-45 has a crucial role in maintaining muscle sarcomeres during aging in C. elegans

This study shows that UNC-45 is essential for maintaining muscle sarcomeres in C. elegans during aging, with its loss leading to sarcopenia through myosin degradation.

Investigating the correlation of muscle function tests and sarcomere organization in C. elegans

This study investigates the relationship between muscle function and sarcomere organization in C. elegans using two assays, finding that mutants with sarcomere defects show reduced muscle strength and that combined assays improve phenotyping.

Conformational changes in twitchin kinase in vivo revealed by FRET imaging of freely moving C. elegans

This study uses FRET imaging in C. elegans to show stretch-induced conformational changes in twitchin kinase during muscle activity.

A Region of UNC-89 (obscurin) Lying Between Two Protein Kinase Domains is a Highly Elastic Spring Required for Proper Sarcomere Assembly

This paper identifies a highly elastic interkinase region in UNC-89 essential for sarcomere assembly, showing that its deletion causes sarcomere disorganization and locomotion defects in C. elegans.

Mutational analysis of the structure and function of the chaperone domain of UNC-45B

This paper investigates the chaperone function of UNC-45B's UCS domain by engineering mutations and analyzing their effects on structure, stability, and sarcomere organization in C. elegans and human cataract.