Mitochondrial respiration contributes to the interferon gamma response in antigen presenting cells
M. Kiritsy, D. Mott, S. M. Behar, C. M. Sassetti, A. J. Olive
This study identifies mitochondrial respiration as essential for the interferon gamma response in antigen presenting cells, showing that complex I inhibition blocks T cell activation.
bioRxiv · Nov 22, 2020Immunology