Development of a NanoBRET assay for evaluation of 14-3-3σ molecular glues
H. R. Vickery, J. M. Virta, M. Konstantinidou, M. R. Arkin
The paper develops a NanoBRET assay to evaluate molecular glues targeting 14-3-3σ client proteins in living cells, showing EC50 values consistent with in vitro measurements.
bioRxiv · Dec 31, 2023Cell Biology