Molecular features driving condensate formation and gene expression by the BRD4-NUT fusion oncoprotein are overlapping but distinct
M. Kosno, S. L. Currie, A. Kumar, C. Xing, M. K. Rosen
This study identifies molecular features of BRD4-NUT and its interaction with p300 that drive condensate formation and gene expression, showing overlapping yet distinct roles of p300 domains.
bioRxiv · May 11, 2023Cell Biology