Mapping local and global liquid-liquid phase behavior in living cells using light-activated multivalent seeds
D. Bracha, M. T. Walls, M.-T. Wei, L. Zhu, M. Kurian, J. E. Toettcher, C. P. Brangwynne
This study maps intracellular phase separation behavior using an optogenetic system, showing localized phase separation can occur through diffusive capture of protein ligands.
bioRxiv · Mar 16, 2018Biophysics