Author

M. L. Hossen

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biophysics· 2 Cell Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:host-pathogen & immune response· 3 Approach:experimental assay· 2 Organism:virus· 2 Approach:comparative / phylogenetic analysis· 1 Organism:human· 1 Assay:structural biology· 1

Frequent Co-Authors

P. P. Chapagain· 3 shared P. Baral· 2 shared B. Gerstman· 1 shared B. S. Gerstman· 1 shared D. Nader· 1 shared G. Bix· 1 shared G. Narasimhan· 1 shared N. Bhattarai· 1 shared

Activity by Year

2021-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 22 mutual co-author links

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3 shared papersBiophysics

P. P. Chapagain

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Author profile →

3 papers

Recent·Most cited

Significance of the RBD mutations in the SARS-CoV-2 Omicron: from spike opening to antibody escape and cell attachment

M. L. Hossen, P. Baral, T. Sharma, B. S. Gerstman, P. P. Chapagain

This study computationally examines how Omicron's RBD mutations affect its structure, ACE2 binding, and antibody evasion, suggesting enhanced infectivity and immune escape.

bioRxiv · Jan 21, 2022Biophysics

A dual-receptor mechanism between integrins and ACE2 widens SARS-CoV-2 tissue tropism

D. Nader, T. E. Gressett, M. L. Hossen, P. P. Chapagain, S. W. Kerrigan, G. Bix

The paper investigates a dual-receptor mechanism involving integrins and ACE2 for SARS-CoV-2 entry and signaling, highlighting integrin's role in expanding tissue tropism and inflammation.

bioRxiv · Jan 2, 2022 · PreprintCell Biology

Mutation-induced Changes in the Receptor-binding Interface of the SARS-CoV-2 Delta Variant B.1.617.2 and Implications for Immune Evasion

P. Baral, N. Bhattarai, M. L. Hossen, V. Stebliankin, B. Gerstman, G. Narasimhan, P. P. Chapagain

The paper examines structural changes in the Delta variant's receptor-binding interface and their impact on immune evasion by neutralizing antibodies.

bioRxiv · Jul 17, 2021Biophysics