Author

M. L. Lozen

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Research Focus:protein folding & dynamics· 1 Research Focus:protein structure prediction· 1 Assay:structural biology· 1

Frequent Co-Authors

A. Ke· 1 shared C. Hu· 1 shared M. T. Myers· 1 shared X. Zhou· 1 shared Y. Zhang· 1 shared Z. Hou· 1 shared

Activity by Year

2023-2023 · peak 1/yr

Co-Author Collaboration Network

6 top collaborators · 15 mutual co-author links

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1 shared paperBiochemistry

A. Ke

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1 paper

Recent·Most cited

Exploiting Activation and Inactivation Mechanisms in Type I-C CRISPR-Cas3 for Genome Editing Applications

C. Hu, M. T. Myers, X. Zhou, Z. Hou, M. L. Lozen, Y. Zhang, A. Ke

This study defines the DNA binding and cleavage mechanisms of Type I-C CRISPR-Cas3 using cryo-EM and identifies anti-CRISPR proteins that inhibit its activity in human cells.

bioRxiv · Aug 5, 2023Biochemistry