Author

M. L. O'Mara

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Biophysics· 1

Signature Assays, Organisms & Methods

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Research Focus:cell signaling & trafficking· 1 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:drug response / drug discovery· 1 Assay:electrophysiology· 1 Approach:experimental assay· 1 Organism:human· 1 Approach:mechanistic / dynamical model· 1 Research Focus:protein folding & dynamics· 1

Frequent Co-Authors

K. A. Wilson· 2 shared L. Wang· 1 shared R. J. Vandenberg· 1 shared S. N. Mostyn· 1 shared S. Shimmon· 1 shared T. Rawling· 1 shared Y. Lin· 1 shared Z. J. Frangos· 1 shared

Activity by Year

2020-2021 · peak 1/yr

Co-Author Collaboration Network

8 top collaborators · 18 mutual co-author links

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2 shared papersBiophysics

K. A. Wilson

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2 papers

Recent·Most cited

Lipid fingerprints are similar between SLC6 transporters in the neuronal membrane

K. A. Wilson, L. Wang, Y. Lin, M. L. O'Mara

The paper uses molecular dynamics simulations to analyze lipid fingerprints of SLC6 transporters in neuronal membranes, finding that lipid composition and interactions vary between transporters and affect membrane properties.

bioRxiv · Jan 20, 2021 · PreprintBiophysics

The inhibitory activity of glycine transporter 2 targeting bioactive lipid analgesics are influenced by formation of a deep lipid cavity

K. A. Wilson, S. N. Mostyn, Z. J. Frangos, S. Shimmon, T. Rawling, R. J. Vandenberg, M. L. O'Mara

This study investigates how N-acyl amino acids inhibit GlyT2 by binding to an allosteric site, showing that stereochemistry, tail length, and double bond position enhance inhibition through deep penetration into the binding pocket.

bioRxiv · Sep 10, 2020 · PreprintBiochemistry